What is precipitated withdrawal?
Precipitated withdrawal is a sudden and intense onset of withdrawal symptoms that can happen when Suboxone (buprenorphine-naloxone) is taken too soon after your last use of an opioid. It is caused by the buprenorphine displacing the opioid from your receptors before your system has had enough time to clear it.
Unlike normal withdrawal, which comes on gradually, precipitated withdrawal tends to feel more abrupt and can be more uncomfortable. The good news is that it is temporary and manageable.
How do I know if I am experiencing precipitated withdrawal?
Symptoms typically begin within 30 to 90 minutes of taking your first dose of Suboxone. They may include:
- Sudden and intense sweating, chills, or goosebumps
- Nausea, vomiting, or diarrhea
- Muscle aches, cramping, or restlessness
- Anxiety, agitation, or feeling unable to sit still
- Yawning or teary eyes
If your symptoms started rapidly after taking Suboxone and feel more severe than expected, contact our Patient Support team right away.