Safest option: Use a DEA-authorized drug take-back location. Find one at the DEA's website or call 1-800-882-9539. Many pharmacies and police stations have drop boxes.
If no take-back is available: Mix medication with coffee grounds, dirt, or cat litter; place in a sealed bag; remove personal info from the label; discard in your rubbish bin.
Suboxone: On the FDA flush list — flushing is specifically approved when no take-back is available, due to the risk of accidental exposure to children.
Do not flush other medications unless they appear on the FDA flush list.