Who should not take hormone therapy?

Hormone therapy is not appropriate for everyone. Your clinician will review your health history carefully before prescribing.

Generally not recommended if you have:

  • A personal history of breast, ovarian, or endometrial cancer (especially hormone-sensitive types)
  • A history of blood clots (DVT or pulmonary embolism)
  • A history of stroke or heart attack
  • Active liver disease
  • Unexplained vaginal bleeding
  • A known allergy to any component of the therapy

Special consideration cases:

  • BRCA1/BRCA2 mutation carriers: May still be appropriate in some situations — requires detailed discussion with your clinician and potentially a breast oncologist.
  • Strong family history of breast cancer: Not an automatic contraindication — requires individual risk assessment.
  • Cardiovascular disease: Transdermal forms (patch/gel) may be safer than oral tablets — discuss with your clinician.

If you're unsure, a consultation with a QuickMD clinician is the best place for a personalized assessment.

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