What are the risks of NOT taking hormone therapy?

Choosing not to use hormone therapy is a valid decision, and it's worth understanding what declining treatment may mean for your body.

Short-term quality-of-life impact: Menopause symptoms — hot flashes, sleep loss, mood changes, brain fog, vaginal dryness — may persist for several years and can substantially affect daily life, work, and relationships.

Long-term risks of estrogen loss:

  • Bone density loss (osteoporosis): Bone loss accelerates significantly after menopause. Women who forgo hormone therapy may need bone-protective medications later.
  • Cardiovascular risk: Estrogen has protective effects on blood vessels. Some evidence links estrogen loss to increased cardiovascular risk.
  • Genitourinary syndrome: Vaginal dryness, recurrent UTIs, and urinary urgency worsen over time if untreated.
  • Cognitive changes: Some evidence suggests estrogen plays a role in brain health.

Alternative approaches: Non-hormonal options exist for some symptoms — vaginal moisturizers, paroxetine for hot flashes, and lifestyle approaches. Discuss alternatives with your clinician.

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